GTX68076-PRO
Human PIG3 protein, His tag
Cannot supply to this region.
- SKU:
- GTX68076-PRO
- Additional Names:
- tumor protein p53 inducible protein 3 , PIG3
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, no preservatives.
- Immunogen:
- tumor protein p53 inducible protein 3
- Species:
- Human
- Uniprot:
- Q53FA7
- Synonyms:
- p53-induced gene 3 protein;PIG3;quinone oxidoreductase homolog;quinone oxidoreductase PIG3;Tumor protein p53-inducible protein 3
- Extra Details:
- The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
- Shipping Conditions:
- Dry Ice