Human SOCS3 protein, His tag

Cannot supply to this region.

SKU:: GTX68020-PRO
Additional Names:: suppressor of cytokine signaling 3 , ATOD4 , CIS3 , Cish3 , SOCS-3 , SSI-3 , SSI3
Concentration:: 0.5 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservatives.
Immunogen:: suppressor of cytokine signaling 3
Species:: Human
Uniprot:: O14543
Synonyms:: ATOD4;CIS3;Cish3;cytokine-inducible SH2 protein 3;SOCS-3;SSI-3;SSI3;STAT-induced STAT inhibitor 3;suppressor of cytokine signaling 3
Extra Details:: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]