Human RAB7A protein, His tag

Cannot supply to this region.

SKU:: GTX67953-PRO
Additional Names:: RAB7A, member RAS oncogene family , PRO2706 , RAB7
Concentration:: 0.5 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 100mM NaCl, 30% Glycerol, 1mM DTT, no preservatives.
Immunogen:: RAB7A, member RAS oncogene family
Species:: Human
Uniprot:: P51149
Synonyms:: CMT2B;PRO2706;RAB7;RAB7, member RAS oncogene family;Ras-associated protein RAB7;ras-related protein Rab-7a
Extra Details:: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]