GTX67903-PRO
Human Translin protein
Cannot supply to this region.
- SKU:
- GTX67903-PRO
- Additional Names:
- translin , BCLF-1 , C3PO , RCHF1 , REHF-1 , TBRBP , TRSLN
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- translin
- Species:
- Human
- Uniprot:
- Q15631
- Synonyms:
- BCLF-1;C3PO;component 3 of promoter of RISC;RCHF1;recombination hotspot associated factor;recombination hotspot-binding protein;REHF-1;TBRBP;testis brain-RNA binding protein;translin;TRSLN
- Extra Details:
- This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
- Shipping Conditions:
- Dry Ice