GTX67877-PRO
Human TCF4 protein, His tag
Cannot supply to this region.
- SKU:
- GTX67877-PRO
- Additional Names:
- transcription factor 4 , E2-2 , FECD3 , ITF-2 , ITF2 , PTHS , SEF-2 , SEF2 , SEF2-1 , SEF2-1A , SEF2-1B , SEF2-1D , TCF-4 , bHLHb19
- Concentration:
- 0.5 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, no preservatives.
- Immunogen:
- transcription factor 4
- Species:
- Human
- Uniprot:
- P15884
- Synonyms:
- bHLHb19;CDG2T;class B basic helix-loop-helix protein 19;E2-2;FECD3;immunoglobulin transcription factor 2;ITF-2;ITF2;PTHS;SEF-2;SEF2;SEF2-1;SEF2-1A;SEF2-1B;SEF2-1D;SL3-3 enhancer factor 2;TCF-4;transcription factor 4
- Extra Details:
- This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]
- Shipping Conditions:
- Dry Ice