GTX67669-PRO
Human AMPK beta 2 protein, His tag
Cannot supply to this region.
- SKU:
- GTX67669-PRO
- Additional Names:
- protein kinase AMP-activated non-catalytic subunit beta 2
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 2M Urea, 10% Glycerol, no preservatives.
- Immunogen:
- protein kinase AMP-activated non-catalytic subunit beta 2
- Species:
- Human
- Uniprot:
- O43741
- Synonyms:
- 5'-AMP-activated protein kinase subunit beta-2;5'-AMP-activated protein kinase, beta-2 subunit;AMP-activated protein kinase beta 2 non-catalytic subunit;AMPK beta 2;AMPK beta-2 chain;AMPK subunit beta-2;protein kinase, AMP-activated, beta 2 non-catalytic subunit
- Extra Details:
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
- Shipping Conditions:
- Dry Ice