GTX67551-PRO
Human MGMT protein, His tag
Cannot supply to this region.
- SKU:
- GTX67551-PRO
- Additional Names:
- O-6-methylguanine-DNA methyltransferase
- Concentration:
- 0.5 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- O-6-methylguanine-DNA methyltransferase
- Species:
- Human
- Uniprot:
- B4DEE8
- Synonyms:
- 6-O-methylguanine-DNA methyltransferase;methylated-DNA--protein-cysteine methyltransferase;methylguanine-DNA methyltransferase;O-6-methylguanine-DNA-alkyltransferase;O6-methylguanine-DNA methyltransferase
- Extra Details:
- Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
- Shipping Conditions:
- Dry Ice