GTX67214-PRO
Human BIN1 protein, His tag
Cannot supply to this region.
- SKU:
- GTX67214-PRO
- Additional Names:
- bridging integrator 1 , AMPH2 , AMPHL , CNM2 , SH3P9
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- bridging integrator 1
- Species:
- Human
- Uniprot:
- Q9BTH3
- Synonyms:
- AMPH2;amphiphysin II;amphiphysin-like protein;AMPHL;box dependant MYC interacting protein 1;box-dependent myc-interacting protein 1;CNM2;myc box-dependent-interacting protein 1;SH3P9
- Extra Details:
- This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016]
- Shipping Conditions:
- Dry Ice