Human ALAD protein, His tag

Cannot supply to this region.

SKU:: GTX67208-PRO
Additional Names:: aminolevulinate dehydratase , ALADH , PBGS
Concentration:: 1 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, no preservatives.
Immunogen:: aminolevulinate dehydratase
Species:: Human
Uniprot:: P13716
Synonyms:: ALADH;aminolevulinate, delta-, dehydratase;delta-aminolevulinic acid dehydratase;PBGS;porphobilinogen synthase;testicular tissue protein Li 95
Extra Details:: The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]