GTX67201-PRO
Human ADSL protein, His tag
Cannot supply to this region.
- SKU:
- GTX67201-PRO
- Additional Names:
- adenylosuccinate lyase , AMPS , ASASE , ASL
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 40% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- adenylosuccinate lyase
- Species:
- Human
- Uniprot:
- P30566
- Synonyms:
- adenylosuccinase;adenylosuccinate lyase;AMPS;ASASE;ASL
- Extra Details:
- The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
- Shipping Conditions:
- Dry Ice