Human PAI-1 protein, His tag (active)

Cannot supply to this region.

SKU:: GTX67102-PRO
Additional Names:: serpin family E member 1 , PAI , PAI-1 , PAI1 , PLANH1
Application:: FuncS
Concentration:: 1 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 50mM NaAc, 100mM NaCl, 10% Glycerol, no preservatives.
Immunogen:: serpin family E member 1
Species:: Human
Uniprot:: P05121
Synonyms:: endothelial plasminogen activator inhibitor;PAI;PAI-1;PAI1;PLANH1;plasminogen activator inhibitor 1;serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;serpin E1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Extra Details:: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]