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GTX66984-PRO

Human EPO receptor protein, His tag (active)

Cannot supply to this region.

SKU:
GTX66984-PRO
Additional Names:
erythropoietin receptor , EPO-R
Application:
FuncS
Concentration:
0.5 mg/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
PBS, 10% Glycerol, no preservatives.
Immunogen:
erythropoietin receptor
Species:
Human
Uniprot:
P19235
Synonyms:
EPO-R;erythropoietin receptor;truncated erythropoietin receptor
Extra Details:
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Shipping Conditions:
Dry Ice