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GTX66973-PRO

Human DUSP10 protein, His tag (active)

Cannot supply to this region.

SKU:
GTX66973-PRO
Additional Names:
dual specificity phosphatase 10 , MKP-5 , MKP5
Application:
FuncS
Concentration:
0.25 mg/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
20mM Tris-HCl, 200mM NaCl, 50% Glycerol, 2mM DTT, no preservatives.
Immunogen:
dual specificity phosphatase 10
Species:
Human
Uniprot:
Q9Y6W6
Synonyms:
dual specificity phosphatase MKP-5;dual specificity protein phosphatase 10;map kinase phosphatase 5;mitogen-activated protein kinase phosphatase 5;MKP-5;MKP5;serine/threonine specific protein phosphatase
Extra Details:
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Shipping Conditions:
Dry Ice