Human AKR1C3 protein (active)

Cannot supply to this region.

SKU:: GTX66915-PRO
Additional Names:: aldo-keto reductase family 1 member C3 , DD3 , DDX , HA1753 , HAKRB , HAKRe , HSD17B5 , PGFS , hluPGFS
Application:: FuncS
Concentration:: 1 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
Immunogen:: aldo-keto reductase family 1 member C3
Species:: Human
Uniprot:: P42330
Synonyms:: 17-beta-hydroxysteroid dehydrogenase type 5;3-alpha hydroxysteroid dehydrogenase, type II;3-alpha-HSD type II, brain;3-alpha-hydroxysteroid dehydrogenase type 2;aldo-keto reductase family 1 member C3;chlordecone reductase homolog HAKRb;DD3;DDX;dihydrodiol dehydrogenase 3;Dihydrodiol dehydrogenase type I;dihydrodiol dehydrogenase X;HA1753;HAKRB;HAKRe;hluPGFS;HSD17B5;indanol dehydrogenase;PGFS;prostaglandin F synthase;testosterone 17-beta-dehydrogenase 5;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;type IIb 3-alpha hydroxysteroid dehydrogenase
Extra Details:: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Shipping Conditions:: Dry Ice