GTX66781
Cathepsin L antibody
Cannot supply to this region.
- SKU:
- GTX66781
- Additional Names:
- cathepsin L , CATL , CTSL1 , MEP
- Application:
- WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to residues in Human CTSL1
- Uniprot:
- P07711
- Synonyms:
- Cathepsin L;cathepsin L1;CATL;CTSL1;major excreted protein;MEP;procathepsin L
- Extra Details:
- The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
- Shipping Conditions:
- Blue Ice