GTX66658
MED1 antibody
Cannot supply to this region.
- SKU:
- GTX66658
- Additional Names:
- mediator complex subunit 1 , CRSP1 , CRSP200 , DRIP205 , DRIP230 , PBP , PPARBP , PPARGBP , RB18A , TRAP220 , TRIP2
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- Synthetic peptide, corresponding to amino acids 664-720 of Human TRAP220.
- Uniprot:
- Q15648
- Synonyms:
- activator-recruited cofactor 205 kDa component;ARC205;CRSP1;CRSP200;DRIP205;DRIP230;Mediator complex subunit 1;mediator of RNA polymerase II transcription subunit 1;p53 regulatory protein RB18A;PBP;peroxisome proliferator-activated receptor-binding protein;PPAR-binding protein;PPARBP;PPARG binding protein;PPARGBP;RB18A;thyroid hormone receptor-associated protein complex 220 kDa component;thyroid hormone receptor-associated protein complex component TRAP220;thyroid receptor interacting protein 2;Thyroid receptor-interacting protein 2;TR-interacting protein 2;TRAP220;TRIP-2;TRIP2;vitamin D receptor-interacting protein 230 kD;vitamin D receptor-interacting protein complex component DRIP205
- Extra Details:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice