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  2. Polyclonal

GTX66634

XRCC1 antibody

Cannot supply to this region.

SKU:
GTX66634
Additional Names:
X-ray repair cross complementing 1 , RCC , SCAR26
Application:
WB, IHC-P
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 0.05% Sodium azide.
Immunogen:
Synthetic peptide, corresponding to amino acids 520-570 of Human XRCC1.
Uniprot:
P18887
Synonyms:
DNA repair protein XRCC1;RCC;SCAR26;X-ray repair complementing defective repair in Chinese hamster cells 1;X-ray repair cross-complementing protein 1
Extra Details:
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice