GTX66478
ALAS-H antibody
Cannot supply to this region.
- SKU:
- GTX66478
- Additional Names:
- 5'-aminolevulinate synthase 1 , ALAS , ALAS-H , ALAS3 , ALASH , MIG4
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1).
- Uniprot:
- P13196
- Synonyms:
- 5-aminolevulinate synthase, nonspecific, mitochondrial;5-aminolevulinic acid synthase 1;ALAS;ALAS-H;ALAS3;ALASH;aminolevulinate, delta-, synthase 1;delta-ALA synthase 1;delta-aminolevulinate synthase 1;MIG4;migration-inducing protein 4
- Extra Details:
- This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
- Shipping Conditions:
- Blue Ice