GTX66456
RNMTL1 antibody
Cannot supply to this region.
- SKU:
- GTX66456
- Additional Names:
- mitochondrial rRNA methyltransferase 3 , RMTL1 , RNMTL1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-420 of human MRM3 (NP_060616.1).
- Uniprot:
- Q9HC36
- Synonyms:
- 16S rRNA (guanosine(1370)-2'-O)-methyltransferase;16S rRNA [Gm1370] 2'-O-methyltransferase;putative RNA methyltransferase;RMTL1;RNA methyltransferase like 1;RNA methyltransferase-like protein 1;RNMTL1;rRNA methyltransferase 3, mitochondrial
- Extra Details:
- Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
- Shipping Conditions:
- Blue Ice