YTHDC2 antibody

Cannot supply to this region.

SKU:: GTX66320
Additional Names:: YTH domain containing 2 , CAHL , hYTHDC2
Application:: WB, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant funsion protein containing a sequence corresponding to amino acids 1131-1430 of human YTHDC2 (NP_073739.3).
Uniprot:: Q9H6S0
Synonyms:: 3'-5' RNA helicase YTHDC2;CAHL;CsA-associated helicase-like protein;hYTHDC2;probable ATP-dependent RNA helicase YTHDC2;YTH domain-containing protein 2
Extra Details:: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]