GTX66301
IBTK antibody
Cannot supply to this region.
- SKU:
- GTX66301
- Additional Names:
- inhibitor of Bruton tyrosine kinase , BTBD26 , BTKI
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 900-1200 of human IBTK (NP_056340.2).
- Uniprot:
- Q9P2D0
- Synonyms:
- Bruton agammaglobulinemia tyrosine kinase inhibitor;BTBD26;BTK-binding protein;BTKI;inhibitor of Bruton tyrosine kinase;inhibitor of Bruton's tyrosine kinase-alpha;inhibitor of Bruton's tyrosine kinase-beta;inhibitor of Bruton's tyrosine kinase-gamma
- Extra Details:
- Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
- Shipping Conditions:
- Blue Ice