GTX65985
CYP46A1 antibody
Cannot supply to this region.
- SKU:
- GTX65985
- Additional Names:
- cytochrome P450 family 46 subfamily A member 1 , CP46 , CYP46
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 24-280 of human CYP46A1 (NP_006659.1).
- Uniprot:
- Q9Y6A2
- Synonyms:
- CH24H;cholesterol 24-hydroxylase;cholesterol 24-monooxygenase;cholesterol 24S-hydroxylase;CP46;CYP46;cytochrome P450 46A1;cytochrome P450, family 46, subfamily A, polypeptide 1;cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice