GTX65954
Rent2 antibody
Cannot supply to this region.
- SKU:
- GTX65954
- Additional Names:
- UPF2 regulator of nonsense mediated mRNA decay , HUPF2 , RENT2 , smg-3
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1153-1272 of human UPF2 (NP_542166.1).
- Uniprot:
- Q9HAU5
- Synonyms:
- FRS2/UPF2/LEMD3 fusion;HUPF2;LEMD3/UPF2 fusion;nonsense mRNA reducing factor 2;regulator of nonsense transcripts 2;RENT2;smg-3;smg-3 homolog, nonsense mediated mRNA decay factor;up-frameshift suppressor 2 homolog;UPF2 regulator of nonsense transcripts homolog;yeast Upf2p homolog
- Extra Details:
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice