TAX1BP3 antibody

Cannot supply to this region.

SKU:: GTX64958
Additional Names:: Tax1 binding protein 3 , TIP-1 , TIP1
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant fusion protein containing a sequence corresponding to amino acids 1-124 of human TAX1BP3 (NP_055419.1).
Uniprot:: O14907
Synonyms:: glutaminase-interacting protein 3;Tax interaction protein 1;tax-interacting protein 1;Tax1 (human T-cell leukemia virus type I) binding protein 3;tax1-binding protein 3;TIP-1;TIP1
Extra Details:: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]

Shipping Conditions:: Blue Ice