IRF4 / MUM1 antibody [HL5982]

Cannot supply to this region.

SKU:: GTX647596
Additional Names:: interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment of human IRF4 / MUM1.
Clone:: HL5982
Uniprot:: Q15306
Synonyms:: interferon regulatory factor 4;LSIRF;lymphocyte-specific interferon regulatory factor;multiple myeloma oncogene 1;MUM1;NF-EM5;SHEP8
Extra Details:: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]