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  2. Polyclonal

GTX64702

SBDS antibody

Cannot supply to this region.

SKU:
GTX64702
Additional Names:
SBDS ribosome maturation factor , CGI-97 , SDS , SWDS
Application:
WB, IHC-P, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SBDS (NP_057122.2).
Uniprot:
Q9Y3A5
Synonyms:
CGI-97;ribosome maturation protein SBDS;SBDS, ribosome assembly guanine nucleotide exchange factor;SDO1;SDS;Shwachman-Bodian-Diamond syndrome protein;SWDS
Extra Details:
This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jan 2017]
Shipping Conditions:
Blue Ice