GTX64693
Hairless antibody
Cannot supply to this region.
- SKU:
- GTX64693
- Additional Names:
- HR lysine demethylase and nuclear receptor corepressor , ALUNC , AU , HSA277165 , HYPT4 , MUHH , MUHH1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 200-480 of human HR (NP_005135.2).
- Uniprot:
- O43593
- Synonyms:
- [histone H3]-dimethyl-L-lysine(9) demethylase hairless;ALUNC;AU;hair growth associated;hairless homolog;HSA277165;HYPT4;lysine-specific demethylase hairless;MUHH;MUHH1;protein hairless
- Extra Details:
- This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
- Shipping Conditions:
- Blue Ice