GTX646272
NTSR2 antibody [HL5590]
Cannot supply to this region.
- SKU:
- GTX646272
- Additional Names:
- neurotensin receptor 2 , NTR2
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Intracellular domain of human NTSR2. The exact sequence is proprietary.
- Clone:
- HL5590
- Uniprot:
- O95665
- Synonyms:
- levocabastine-sensitive neurotensin receptor;neurotensin receptor type 2;neurotensin receptor, type 2;NT-R-2;NTR2
- Extra Details:
- The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice