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  2. Polyclonal

GTX64564

HSD3a antibody

Cannot supply to this region.

SKU:
GTX64564
Additional Names:
aldo-keto reductase family 1 member C4 , 3-alpha-HSD , C11 , CDR , CHDR , DD-4 , DD4 , HAKRA
Application:
WB
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C4 (NP_001809.3).
Uniprot:
P17516
Synonyms:
3-alpha-HSD;3-alpha-HSD1;3-alpha-hydroxysteroid dehydrogenase type I;3alpha-hydroxysteroid 3-dehydrogenase;aldo-keto reductase family 1 member C4;C11;CDR;CHDR;Chlordecone reductase;chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4;DD-4;DD4;Dihydrodiol dehydrogenase 4;dihydrodiol dehydrogenase isozyme DD4;HAKRA;type I 3-alpha-hydroxysteroid dehydrogenase
Extra Details:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice