CYP1A2 antibody

Cannot supply to this region.

SKU:: GTX64497
Additional Names:: cytochrome P450 family 1 subfamily A member 2 , CP12 , CYPIA2 , P3-450 , P450(PA)
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human, Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Mouse, Rat
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant fusion protein containing a sequence corresponding to amino acids 205-305 of human CYP1A2 (NP_000752.2).
Uniprot:: P05177
Synonyms:: aryl hydrocarbon hydroxylase;cholesterol 25-hydroxylase;CP12;CYPIA2;cytochrome P(3)450;cytochrome P450 1A2;cytochrome P450 4;cytochrome P450-P3;cytochrome P450, family 1, subfamily A, polypeptide 2;cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2;dioxin-inducible P3-450;flavoprotein-linked monooxygenase;hydroperoxy icosatetraenoate dehydratase;microsomal monooxygenase;P3-450;P450 form 4;P450(PA);xenobiotic monooxygenase
Extra Details:: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice