GTX64473
TRAF3 antibody
Cannot supply to this region.
- SKU:
- GTX64473
- Additional Names:
- TNF receptor associated factor 3 , CAP-1 , CAP1 , CD40bp , CRAF1 , IIAE5 , LAP1 , RNF118
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- A synthetic peptide of human TRAF3
- Uniprot:
- Q13114
- Synonyms:
- CAP-1;CAP1;CD40 associated protein 1;CD40 binding protein;CD40 receptor associated factor 1;CD40 receptor-associated factor 1;CD40-binding protein;CD40bp;CRAF1;IIAE5;LAP1;LMP1-associated protein 1;RING-type E3 ubiquitin transferase TRAF3;RNF118;TNF receptor-associated factor 3
- Extra Details:
- The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]
- Shipping Conditions:
- Blue Ice