GTX642573
mGluR1 antibody [HL4127]
Cannot supply to this region.
- SKU:
- GTX642573
- Additional Names:
- glutamate metabotropic receptor 1 , GPRC1A , MGLU1 , MGLUR1 , PPP1R85 , SCA44 , SCAR13
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Extracellular domain of human mGluR1. The exact sequence is proprietary.
- Clone:
- HL4127
- Uniprot:
- Q13255
- Synonyms:
- glutamate receptor, metabotropic 1;GPRC1A;metabotropic glutamate receptor 1;MGLU1;MGLUR1;PPP1R85;protein phosphatase 1, regulatory subunit 85;SCA44;SCAR13
- Extra Details:
- This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Shipping Conditions:
- Blue Ice