![CD11b antibody [HL3097]](https://www.genetex.com/upload/website/prouct_img/normal/GTX640543/GTX640543_45509_20240823_WB_M_Fraction_ub_24090423_767.webp)
![CD11b antibody [HL3097]](https://www.genetex.com/upload/website/prouct_img/normal/GTX640543/GTX640543_T-45453_20240802_IHC-P_M_24081300_176.webp)
![CD11b antibody [HL3097]](https://www.genetex.com/upload/website/prouct_img/normal/GTX640543/GTX640543_T-45453_20240802_IHC-P_R_24081300_924.webp)
GTX640543
CD11b antibody [HL3097]
Cannot supply to this region.
- SKU:
- GTX640543
- Additional Names:
- integrin alpha M , CD11b/CD18 , CR3 , CR3A , Cd11b , F730045J24Rik , Ly-40 , MAC1 , Mac-1 , Mac-1a
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Extracellular domain of mouse CD11b. The exact sequence is proprietary.
- Clone:
- HL3097
- Uniprot:
- P05555
- Synonyms:
- CD11 antigen-like family member B;Cd11b;CD11B (p170);CD11b/CD18;cell surface glycoprotein MAC-1 alpha subunit;cell surface glycoprotein MAC-1 subunit alpha;complement receptor type 3;CR;CR-3 alpha chain;CR3;CR3A;F730045J24Rik;integrin alpha-M;leukocyte adhesion receptor MO1;Ly-4;Ly-40;Mac-;Mac-1;Mac-1 alpha;Mac-1a;MAC1;macrophage antigen alpha
- Extra Details:
- Enables complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development; endocytosis; and positive regulation of neuron death. Acts upstream of or within several processes, including activated T cell proliferation; leukocyte migration; and microglia development. Located in external side of plasma membrane and nucleus. Is integral component of membrane. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including central nervous system; heart; lymphatic vessel; thymus; and yolk sac. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M). [provided by Alliance of Genome Resources, Apr 2022]
- Shipping Conditions:
- Blue Ice