CCR10 antibody [HL2852]

Cannot supply to this region.

SKU:: GTX640123
Additional Names:: C-C motif chemokine receptor 10 , GPR2
Application:: IF, ICC, FuncS
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Synthetic peptide encompassing a sequence within the Extracellular domain human of CCR10. The exact sequence is proprietary.
Clone:: HL2852
Uniprot:: P46092
Synonyms:: C-C chemokine receptor type 10;C-C CKR-10;CC chemokine receptor 10;CC-CKR-10;CCR-10;chemokine (C-C motif) receptor 10;G-protein coupled receptor 2;GPR2
Extra Details:: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Shipping Conditions:: Blue Ice