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![CCR5 antibody [HL2780]](https://www.genetex.com/upload/website/prouct_img/normal/GTX639645/GTX639645_T-45299_20240412_IHC-P_24043002_580.webp)
GTX639645
CCR5 antibody [HL2780]
Cannot supply to this region.
- SKU:
- GTX639645
- Additional Names:
- C-C motif chemokine receptor 5 (gene/pseudogene) , CC-CKR-5 , CCCKR5 , CCR-5 , CD195 , CKR-5 , CKR5 , CMKBR5 , IDDM22
- Application:
- Flow Cytometry, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Intracellular domain of human CCR5. The exact sequence is proprietary.
- Clone:
- HL2780
- Uniprot:
- P51681
- Synonyms:
- C-C chemokine receptor type 5;C-C motif chemokine receptor 5 A159A;CC-CKR-5;CCCKR5;CCR-5;CD195;chemokine (C-C motif) receptor 5;chemokine receptor CCR5;chemokine recptor CCR5 Delta32;chemr13;CKR-5;CKR5;CMKBR5;HIV-1 fusion coreceptor;IDDM22;mutant C-C motif chemokine receptor
- Extra Details:
- This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015]
- Shipping Conditions:
- Blue Ice