MSH3 antibody [HL2546]

Cannot supply to this region.

SKU:: GTX638918
Additional Names:: mutS homolog 3 , DUP , FAP4 , MRP1
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment of human MSH3
Clone:: HL2546
Uniprot:: P20585
Synonyms:: divergent upstream protein;DNA mismatch repair protein Msh3;DUP;epididymis secretory sperm binding protein;FAP4;hMSH3;mismatch repair protein 1;MRP1
Extra Details:: The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]