YTHDC2 antibody [HL1916]

Cannot supply to this region.

SKU:: GTX637665
Additional Names:: YTH domain containing 2 , CAHL , hYTHDC2
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment of human YTHDC2
Clone:: HL1916
Uniprot:: Q9H6S0
Synonyms:: 3'-5' RNA helicase YTHDC2;CAHL;CsA-associated helicase-like protein;hYTHDC2;probable ATP-dependent RNA helicase YTHDC2;YTH domain-containing protein 2
Extra Details:: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]