Wnt4 antibody [HL1889]

Cannot supply to this region.

SKU:: GTX637638
Additional Names:: Wnt family member 4 , SERKAL , WNT-4
Application:: WB, IF, ICC
Concentration:: 2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Fish, Human, Mouse
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment of human Wnt4.
Clone:: HL1889
Uniprot:: P56705
Synonyms:: protein Wnt-4;SERKAL;wingless-type MMTV integration site family, member 4;WNT-4
Extra Details:: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice