![WRN antibody [HL1729]](https://www.genetex.com/upload/website/prouct_img/normal/GTX637377/GTX637377_44830_20221014_WB_22101718_529.webp)
![WRN antibody [HL1729]](https://www.genetex.com/upload/website/prouct_img/normal/GTX637377/GTX637377_T-44781_20220902_IHC-P_22101319_241.webp)
GTX637377
WRN antibody [HL1729]
Cannot supply to this region.
- SKU:
- GTX637377
- Additional Names:
- Werner syndrome RecQ like helicase , RECQ3 , RECQL2 , RECQL3
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human WRN. The exact sequence is proprietary.
- Clone:
- HL1729
- Uniprot:
- Q14191
- Synonyms:
- DNA helicase, RecQ-like type 3;exonuclease WRN;recQ protein-like 2;RECQ3;RECQL2;RECQL3;Werner syndrome ATP-dependent helicase;Werner syndrome RecQ like helicase;Werner syndrome, RecQ helicase-like
- Extra Details:
- This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
- Shipping Conditions:
- Blue Ice