C3 antibody [HL1643]

Cannot supply to this region.

SKU:: GTX637224
Additional Names:: complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p
Application:: WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human C3. The exact sequence is proprietary.
Clone:: HL1643
Uniprot:: P01024
Synonyms:: acylation-stimulating protein cleavage product;AHUS5;ARMD9;ASP;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1;C3a;C3a anaphylatoxin;C3b;complement C3;complement component 3;complement component C3a;complement component C3b;CPAMD1;epididymis secretory sperm binding protein Li 62p;HEL-S-62p;prepro-C3
Extra Details:: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Shipping Conditions:: Blue Ice