B-Raf antibody [HL1606]

Cannot supply to this region.

SKU:: GTX637085
Additional Names:: B-Raf proto-oncogene, serine/threonine kinase , B-RAF1 , B-raf , BRAF1 , NS7 , RAFB1
Application:: WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Canine, Human, Mouse, Rat, Feline
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary.
Clone:: HL1606
Uniprot:: P15056
Synonyms:: 94 kDa B-raf protein;B-raf;B-Raf proto-oncogene serine/threonine-protein kinase (p94);B-Raf serine/threonine-protein;B-RAF1;BRAF1;murine sarcoma viral (v-raf) oncogene homolog B1;NS7;p94;proto-oncogene B-Raf;RAFB1;serine/threonine-protein kinase B-raf;v-raf murine sarcoma viral oncogene homolog B;v-raf murine sarcoma viral oncogene homolog B1
Extra Details:: This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]

Shipping Conditions:: Blue Ice