YTHDF2 antibody [HL1354]

Cannot supply to this region.

SKU:: GTX636774
Additional Names:: YTH N6-methyladenosine RNA binding protein 2 , CAHL , HGRG8 , NY-REN-2
Application:: WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human YTHDF2. The exact sequence is proprietary.
Clone:: HL1354
Uniprot:: Q9Y5A9
Synonyms:: 9430020E02Rik;CAHL;CLL-associated antigen KW-14;DF2;HGRG8;high-glucose-regulated protein 8;NY-REN-2;renal carcinoma antigen NY-REN-2;YTH domain family, member 2;YTH domain-containing family protein 2;YTH N(6)-methyladenosine RNA binding protein 2
Extra Details:: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]

Shipping Conditions:: Blue Ice