CDC25B antibody [EPR3459(2)]

Cannot supply to this region.

SKU:: GTX63329
Additional Names:: cell division cycle 25B
Application:: WB, IP
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Crude Cell Culture Supernatant
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: Buffer, 0.05% BSA, 50% Glycerol, 0.01% Sodium azide.
Immunogen:: Synthetic peptide corresponding to residues in human Cdc25B
Clone:: EPR3459(2)
Uniprot:: P30305
Synonyms:: CDC25 homolog B;dual specificity phosphatase Cdc25B;M-phase inducer phosphatase 2
Extra Details:: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]