IL10 antibody [GT5111]

Cannot supply to this region.

SKU:: GTX632359
Additional Names:: interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF
Application:: WB, IHC-P, IHC-Fr
Concentration:: 1.19 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human IL10. The exact sequence is proprietary.
Clone:: GT5111
Uniprot:: P22301
Synonyms:: CSIF;cytokine synthesis inhibitory factor;GVHDS;IL-10;IL10A;interleukin-10;T-cell growth inhibitory factor;TGIF
Extra Details:: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq]

Shipping Conditions:: Blue Ice