UVSSA antibody [GT816]

Cannot supply to this region.

SKU:: GTX629742
Additional Names:: UV stimulated scaffold protein A , KIAA1530 , UVSS3
Application:: WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary.
Clone:: GT816
Uniprot:: Q2YD98
Synonyms:: KIAA1530;UV-stimulated scaffold protein A;UVSS3
Extra Details:: The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]