HMGB1 antibody [GT427]

Cannot supply to this region.

SKU:: GTX629445
Additional Names:: high mobility group box 1 , HMG-1 , HMG1 , HMG3 , SBP-1
Application:: WB, IHC-Fr, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HMGB1. The exact sequence is proprietary.
Clone:: GT427
Uniprot:: P09429
Synonyms:: Amphoterin;High mobility group protein 1;high mobility group protein B1;high-mobility group (nonhistone chromosomal) protein 1;HMG-1;HMG1;HMG3;SBP-1;Sulfoglucuronyl carbohydrate binding protein
Extra Details:: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.