Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Monoclonal

GTX60543

CYP1A1 antibody [6G5]

Cannot supply to this region.

SKU:
GTX60543
Additional Names:
cytochrome P450 family 1 subfamily A member 1 , AHH , AHRR , CP11 , CYP1 , CYPIA1 , P1-450 , P450-C , P450DX
Application:
ELISA, WB, IHC-P
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein G Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 0.05% Sodium azide.
Immunogen:
Purified recombinant fragment of human CYP1A1(AA : 203-461) expressed in E. Coli.
Clone:
6G5
Uniprot:
P04798
Synonyms:
AHH;AHRR;aryl hydrocarbon hydroxylase;CP11;CYP1;CYPIA1;cytochrome P1-450, dioxin-inducible;cytochrome P450 1A1;cytochrome P450 form 6;cytochrome P450-C;cytochrome P450-P1;cytochrome P450, family 1, subfamily A, polypeptide 1;cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1;flavoprotein-linked monooxygenase;hydroperoxy icosatetraenoate dehydratase;P1-450;P450-C;P450DX;xenobiotic monooxygenase
Extra Details:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice