HFE antibody [3F1]

Cannot supply to this region.

SKU:: GTX60503
Additional Names:: homeostatic iron regulator , HFE1 , HH , HLA-H , MVCD7 , TFQTL2
Application:: ELISA, WB, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human HFE expressed in E. Coli.
Clone:: 3F1
Uniprot:: Q30201
Synonyms:: hereditary hemochromatosis protein;hereditary hemochromatosis protein HLA-H;HFE1;HH;high Fe;HLA-H;MHC class I-like protein HFE;MVCD7;TFQTL2
Extra Details:: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]