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  2. Monoclonal

GTX60478

Lamin A antibody [4E7]

Cannot supply to this region.

SKU:
GTX60478
Additional Names:
lamin A/C , CDCD1 , CDDC , CMD1A , CMT2B1 , EMD2 , FPL , FPLD , FPLD2 , HGPS , IDC , LDP1 , LFP , LGMD1B , LMN1 , LMNC , LMNL1 , MADA , PRO1
Application:
ELISA, WB, IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Unpurified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human, Mouse, Rat
Buffer:
Ascites, 0.03% Sodium azide.
Immunogen:
Purified recombinant fragment of human LMNA expressed in E. Coli.
Clone:
4E7
Uniprot:
P02545
Synonyms:
70 kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;epididymis secretory sperm binding protein;FPL;FPLD;FPLD2;HGPS;IDC;lamin;lamin A/C-like 1;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;mandibuloacral dysplasia type A;prelamin-A/C;PRO1;renal carcinoma antigen NY-REN-32
Extra Details:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
Shipping Conditions:
Blue Ice