LIMS1 antibody [5G7]

Cannot supply to this region.

SKU:: GTX60472
Additional Names:: LIM zinc finger domain containing 1 , PINCH , PINCH-1 , PINCH1
Application:: ELISA, Flow Cytometry, WB, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human LIMS1 expressed in E. Coli.
Clone:: 5G7
Uniprot:: P48059
Synonyms:: LIM and senescent cell antigen-like domains 1;LIM and senescent cell antigen-like-containing domain protein 1;LIM-type zinc finger domains 1;particularly interesting new Cys-His protein 1;PINCH;PINCH-1;PINCH1;renal carcinoma antigen NY-REN-48;senescent cell antigen
Extra Details:: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Shipping Conditions:: Blue Ice